The promise of personalized training program.
"The discovery of variants that affect risk for disease could potentially be used in individualized preventive medicine-including diet, Exercise, Lifestyle and pharmaceutical intervention-to maximize the likelihood of staying well".
The language of genetics:
Gene: The term specifically refers to a "Distinct region of the DNA" that acts as a physical and functional unit of the heredity.
- Abbreviated gene name from human written in all "Capitals"
- Abbreviated gene name from other mammals are written with just the "First letter capitalized"
Polymorphism: "Different forms". Difference in one underlying nucleic acid at a specific location and is referred to as "single Nucleotide polymorphism"(or SNP)
Genotype: Unique genomic pattern of each individual encompasses everything from general genomic sequence to specific SNP variant within a specific gene.
Roth's Scenarios:
How genetic information may be used in exercise prescriptions.He proposed 3 scenarios.
Scenario:1
Responder to Exercise: Someone who when put on an exercise training program will increase their aerobic capacity or strength.Approximately 55% of individuals would fall under this category.
Scenario:2
Nonresponder to Exercise: An individual who show "little or no change" with participation in an exercise training program.Approximately 30% and 40% of individuals may fall into this category.It maybe helpful to use this information to modify the exercise prescriptions.
Scenario:3
Negative responder to Exercise: An individual who shows adverse response to exercise training program, including a decrease in aerobic capacity and negative metabolic adaptations.Approxiamtely 5% and 15% of individuals fall into this category.
In the bottom line,
For the 'Negative responder to exercise' population genetic information could contribute significantly to the development of an exercise prescription that would provide health benefits inspite of decrease in aerobic capacity.
Comments
Post a Comment