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Showing posts from April, 2020

Effect of pregnancy on musculoskeletal health and gestational weight gain

Pregnancy: Pregnancy is accompanied by profound physiological changes. Menstrual cycle ceases for the duration of the pregnancy, which is approximately 40 weeks or 9 months. During that time estrogen and progesterone, which are rise continually. Gestation is traditionally divided into three phases or trimesters, each lasting about 3 months. During this time maternal health and behaviors can affect both fetal and maternal outcomes. First trimester: Dedicated to the development of embryo. By 8 weeks embryonic development is complete and major organs and body systems are differentiated. The embryo is now a  fetus. Facial features are evident and external genetalia can be observed. Most importantly, By 8 weeks: Placenta is mature, the umbilical cord is functioning, the circulatory system is well established Placenta become the dominant source of estrogen and progesterone to sustain the pregnancy. By 12 weeks:( @ the end of first trimester) the cardiovascular sy...

Physiology of sleep

Sleep  is defined as  aroused by sensory or other stimuli . There are multiple stages of sleep, form very light sleep to very deep sleep. Types of sleep: Slow-wave sleep: Most sleep during each night is of the slow-wave variety this is  deep, restful sleep  that the person experience during the first hour of sleep. Slow-wave sleep is frequently called  "dreamless sleep". Sometimes dreams and night mare do occur in slow-wave sleep. But  those dreams are not remembered because consolidation of the dreams in memory doesn't occur. REM(Rapid Eye Movement) sleep: Rapid Eye movement sleep occupies  25% of the sleep time  in young adults. Each episode normally  reoccurs about every 90 minutes . This type of sleep is  not so restful , It is usually associated with vivid  dreaming with bodily muscle movement. Muscle tone throughout the body is exceedingly depressed, Indicating strong inhibition of the spinal muscle control a...

Short term energy: The lactic acid system

Resynthesis of the high-energy phosphates must be proceed at a rapid rate to continue intense, short duration exercise. The energy to phosphorylate ADP during such exercise comes mainly from the stored muscle glycogen via anaerobic glycolysis with resulting lactate formation. "Rapid and large accumulation of blood lactate occur during maximal exercise that lasts between 60 and 180 seconds. Decrease the intensity of exercise that decreases the rate of lactate accumulation and final blood lactate". Lactate Accumulation: Blood lactate doesn't accumulate at all levels of exercise. In biochemical terms, energy generated from the oxidation of hydrogen provides the predominant ATP fuel for muscular activity. Any lactate formed in one part of the working muscles becomes rapidly oxidized by muscle fibers with high oxidative capacity in the same muscle When lactate oxidation equals its production, blood lactate level remains stable even though  increases in occur in exe...

Genetic variability in response to Exercise

The promise of personalized training program . "The discovery of variants that affect risk for disease could potentially be used in individualized preventive medicine-including diet, Exercise, Lifestyle and pharmaceutical intervention-to maximize the likelihood of staying well". The language of genetics: Gene: The term specifically refers to a "Distinct region of the DNA" that acts as a physical and functional unit of the heredity. Abbreviated gene name from human written in all "Capitals" Abbreviated gene name from other mammals are written with just the "First letter capitalized" Phenotype: Its a set of measurable characteristics of an organism that are correlated with that organism's genome and its environment. Polymorphism: "Different forms". Difference in one underlying nucleic acid at a specific location and is referred to as "single Nucleotide polymorphism"( or SNP ) Genotype: Unique genomic...

Genetics influences body fat accumulation

Obesity remains a worldwide pandemic. In our modern era, no clear answer exists to a seemingly simple question:  Why have so many people become too fat?  What can be done to reduce the problem?  If you asks the above questions to the healthcare professionals or allied health professionals, No doubt, You will get a tons of answers based on the scientific background and self-experience as well.  Among most of the complex interactions in over fatness. Here, I'm intending to write this article to express my view on how genetics influences body fat accumulation.   Research with specific segments of the population attributes up to 80% of the risk of becoming obese to genetic factors.   For example,   Overweight parents: Newborns with large body weight becomes fat adolescents only when the father or particularly the mother is overweight.  Normal weight parents: Little risks exists for an overweight toddler to g...